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Anabolic testosterone propionate has a short half-life and releases slowly. Testosterone propionate was initially developed by Watson labs and received FDA approval on February 5, 1974. It is a synthetic androstane steroid derivative of testosterone in the form of a 17-propionate ester.2The human formulation of this medication is no longer available, but the over-the-counter version is still available.

Because it is a synthetic androgen and anabolic steroid, testosterone propionate is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). Testosterone propionate was discovered in 1936 and was introduced for medical use in 1937.  It was the first testosterone ester to be marketed, and it was the major form of testosterone used in medicine until about 1960.

According to Petering (2017), hypogonadism (low T), gender dysphoria, and androgen deficiencies can all benefit from testosterone replacement therapy.

As previously stated, testosterone is well-known for its “androgenic” effects on men, such as the growth of body hair and the maintenance of a sex drive. In any case, it has contribution in many physical processes in all kinds of people.

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Your ability to process cholesterol and the strength of your bones are both influenced by testosterone. The way your body makes fat is also related to testosterone. It is interesting to note that people who are overweight or obese tend to have lower levels of it (Nassar, 2021).

According to Snyder (2018), hypogonadism-related symptoms significantly improved in T-treated trial participants. According to Hembree (2017), transgender men who suffer from the anxiety and distress associated with gender dysphoria may also benefit significantly from T.

Testosterone levels naturally fall as men get older. While it could appear to be useful to regulate testosterone to more seasoned men, TRT isn’t authoritatively FDA-endorsed for age-related hypogonadism. However, this group of patients receives off-label prescriptions for testosterone replacement therapy from a large number of healthcare providers (Saad, 2017).

According to Nassar (2022), TRT should be avoided in patients with the following conditions:

Individuals experiencing cardiovascular breakdown or uncontrolled hypertension

Those at expanded risk for respiratory failures

Sorts of bosom disease and prostate malignant growth

Certain blood conditions

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TRT is particularly dangerous for those with heart issues; An official safety notice was issued by the Food and Drug Administration (FDA) of the United States to highlight the potential for heart problems in testosterone users (FDA, 2015).TRT may also make you more likely to have liver problems like hepatic adenomas, which are benign or non-cancerous liver tumors (Nassar, 2022).

Although it is uncommon, injectable or topical testosterone can cause severe allergic reactions as side effects of testosterone replacement therapy. Do not take a second testosterone dose if you experience severe symptoms like hives, swelling, or shortness of breath and seek immediate medical attention.

There is a risk of abuse associated with testosterone, which is a controlled substance .A heart attack or other immediate and potentially fatal health consequences can result from taking testosterone in conjunction with anabolic steroids or taking more than the recommended amount.

Although hormone therapy has the potential to be beneficial in numerous ways, there is a risk of adverse effects, such as